Publications

2017

Tedaldi LM, Pierce M, Wagner GK. Optimised chemical synthesis of 5-substituted UDP-sugars and their evaluation as glycosyltransferase inhibitors. Carbohydr Res. 2012 Dec 15;364:22-7. doi: 10.1016/j.carres.2012.10.009. Epub 2012 Oct 23. PubMed PMID: 23147042.

Zhao P, Stalnaker SH, Wells L. Approaches for site mapping and quantification of O-linked glycopeptides. Methods Mol Biol. 2013;951:229-44. doi: 10.1007/978-1-62703-146-2_15. PubMed PMID: 23296534.

Shajahan A, Supekar NT, Heiss C, Ishihara M, Azadi P. Tool for Rapid Analysis of Glycopeptide by Permethylation via One-Pot Site Mapping and Glycan Analysis. Anal Chem. 2017 Oct 17;89(20):10734-10743. doi: 10.1021/acs.analchem.7b01730. Epub 2017 Oct 2. PubMed PMID: 28921966.

Ranzinger R, Kochut KJ, Miller JA, Eavenson M, Lutteke T, York WS. GLYDE-I : The GLYcan data exchange format. Perspectives in Science. 2017 January; 11:24-30.

Sheikh MO, Halmo SM, Patel S, Middleton D, Takeuchi H, Schafer CM, West CM, Haltiwanger RS, Avci FY, Moremen KW, Wells L.  Rapid screening of sugar-nucleotide donor specificities of putative glycosyltransferases. Glycobiology. 2017 Mar 1;27(3):206-212. doi: 10.1093/glycob/cww114. PubMed PMID: 28177478.

Tiemeyer M, Aoki K, Paulson J, Cummings RD, York WS, Karlsson NG, Lisacek F, Packer NH, Campbell MP, Aoki NP, Fujita A, Matsubara M, Shinmachi D, Tsuchiya S, Yamada I, Pierce M, Ranzinger R, Narimatsu H, Aoki-Kinoshita KF. GlyTouCan: an accessible glycan structure repository. Glycobiology. 2017 Oct 1;27(10):915-919. doi: 10.1093/glycob/cwx066. PubMed PMID: 28922742.

Sheikh MO, Halmo SM, Wells L. Recent advancements in understanding mammalian O-mannosylation. Glycobiology. 2017 Sep 1;27(9):806-819. doi: 10.1093/glycob/cwx062. PubMed PMID: 28810660.

Constable S, Lim JM, Vaidyanathan K, Wells L. O-GlcNAc transferase regulates transcriptional activity of human Oct4. Glycobiology. 2017 Oct 1;27(10):927-937. doi: 10.1093/glycob/cwx055. PubMed PMID: 28922739.

Carroll DJ, O’Sullivan JA, Nix DB, Cao Y, Tiemeyer M, Bochner BS.  Sialic acid-binding immunoglobulin-like lectin 8 (Siglec-8) is an activating receptor mediating β2-integrin-dependent function in human eosinophils. J Allergy Clin Immunol. 2017 Sep 6. pii: S0091- 6749(17)31423-9. doi: 10.1016/j.jaci.2017.08.013. [Epub ahead of print] PubMed PMID: 28888781. [Epub ahead of print]

Middleton DR, Zhang X, Wantuch PL, Ozdilek A, Liu X, LoPilato R, Gangasani N, Bridger R, Wells L, Linhardt RJ, Avci FY. Identification and characterization of the Streptococcus pneumoniae type 3 capsule-specific glycoside hydrolase of Paenibacillus species 32352. Glycobiology. 2018 Feb 1;28(2):90-99. doi: 10.1093/glycob/cwx097. PubMed PMID: 29190349.

Taujale R, Edison A, Kannan N. An evolutionary systems approach to investigate sequence-structure-function relationships in Glycosyltransferases. Glycobiology. 2016; 26(12):1469-1471.

Shah P, Powell AL, Orlando R, Bergmann C, Gutierrez-Sanchez G.  Proteomic analysis of ripening tomato fruit infected by Botrytis cinerea. J Proteome Res. 2012 Apr 6;11(4):2178-92. doi: 10.1021/pr200965c. Epub 2012 Mar 20. PubMed PMID: 22364583; PubMed Central PMCID: PMC4874510.

Moremen KW, Tiemeyer M, Nairn AV. Vertebrate protein glycosylation: diversity, synthesis and function. Nat Rev Mol Cell Biol. 2012 Jun 22;13(7):448-62. doi: 10.1038/nrm3383. Review. PubMed PMID: 22722607; PubMed Central PMCID: PMC3934011.

Talabnin K, Aoki K, Saichua P, Wongkham S, Kaewkes S, Boons GJ, Sripa B, Tiemeyer M. Stage-specific expression and antigenicity of glycoprotein glycans isolated from the human liver fluke, Opisthorchis viverrini. Int J Parasitol. 2013 Jan;43(1):37-50. doi: 10.1016/j.ijpara.2012.10.013. Epub 2012 Nov 19. PubMed PMID: 23174105; PubMed Central PMCID: PMC3547145.

Katoh T, Takase J, Tani Y, Amamoto R, Aoshima N, Tiemeyer M, Yamamoto K, Ashida H. Deficiency of α-glucosidase I alters glycoprotein glycosylation and lifespan in Caenorhabditis elegans. Glycobiology. 2013 Oct;23(10):1142-51. doi: 10.1093/glycob/cwt051. Epub 2013 Jul 7. PubMed PMID: 23836288; PubMed Central PMCID: PMC3766279.

Kumagai T, Katoh T, Nix DB, Tiemeyer M, Aoki K. In-gel β- elimination and aqueous-organic partition for improved O- and sulfoglycomics. Anal Chem. 2013 Sep 17;85(18):8692-9. doi: 10.1021/ac4015935. Epub 2013 Aug 27. PubMed PMID: 23937624; PubMed Central PMCID: PMC4004059.

Boccuto L, Aoki K, Flanagan-Steet H, Chen CF, Fan X, Bartel F, Petukh M, Pittman A, Saul R, Chaubey A, Alexov E, Tiemeyer M, Steet R, Schwartz CE. A mutation in a ganglioside biosynthetic enzyme, ST3GAL5, results in salt & pepper syndrome, a neurocutaneous disorder with altered glycolipid and glycoprotein glycosylation. Hum Mol Genet. 2014 Jan 15;23(2):418-33. doi: 10.1093/hmg/ddt434. Epub 2013 Sep 10. PubMed PMID: 24026681; PubMed Central PMCID: PMC3869362.

Mbua NE, Li X, Flanagan-Steet HR, Meng L, Aoki K, Moremen KW, Wolfert MA, Steet R, Boons GJ. Selective exo-enzymatic labeling of N-glycans on the surface of living cells by recombinant ST6Gal I. Angew Chem Int Ed Engl. 2013 Dec 2;52(49):13012-5. doi: 10.1002/anie.201307095. Epub 2013 Oct 15. PubMed PMID: 24129959; PubMed Central PMCID: PMC3869382.

Live D, Wells L, Boons GJ. Dissecting the molecular basis of the role of the O-mannosylation pathway in disease: α-dystroglycan and forms of muscular dystrophy. Chembiochem. 2013 Dec 16;14(18):2392-402. doi: 10.1002/cbic.201300417. Epub 2013 Nov 7. Review. PubMed PMID: 24318691; PubMed Central PMCID: PMC3938021.

Cummings RD, Pierce JM. The challenge and promise of glycomics. Chem Biol. 2014 Jan 16;21(1):1-15. doi: 10.1016/j.chembiol.2013.12.010. Review. PubMed PMID: 24439204; PubMed Central PMCID: PMC3955176.

Gasimli L, Hickey AM, Yang B, Li G, dela Rosa M, Nairn AV, Kulik MJ, Dordick JS, Moremen KW, Dalton S, Linhardt RJ. Changes in glycosaminoglycan structure on differentiation of human embryonic stem cells towards mesoderm and endoderm lineages. Biochim Biophys Acta. 2014 Jun;1840(6):1993-2003. doi: 10.1016/j.bbagen.2014.01.007. Epub 2014 Jan 9. PubMed PMID: 24412195; PubMed Central PMCID: PMC4004645.

Natunen S, Lampinen M, Suila H, Ritamo I, Pitkänen V, Nairn AV, Räbinä J, Laitinen S, Moremen KW, Reutter W, Valmu L. Metabolic glycoengineering of mesenchymal stromal cells with N- propanoylmannosamine. Glycobiology. 2013 Aug;23(8):1004-12. doi: 10.1093/glycob/cwt039. Epub 2013 May 25. PubMed PMID: 23708401; PubMed Central PMCID: PMC3695754.

Gasimli L, Stansfield HE, Nairn AV, Liu H, Paluh JL, Yang B, Dordick JS, Moremen KW, Linhardt RJ. Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells. Glycoconj J. 2013 Jul;30(5):497-510. doi: 10.1007/s10719- 012-9450-x. Epub 2012 Oct 2. PubMed PMID: 23053635; PubMed Central PMCID: PMC3556377.

Kolarich D, Rapp E, Struwe WB, Haslam SM, Zaia J, McBride R, Agravat S, Campbell MP, Kato M, Ranzinger R, Kettner C, York WS. The minimum information required for a glycomics experiment (MIRAGE) project: improving the standards for reporting mass- spectrometry-based glycoanalytic data. Mol Cell Proteomics. 2013 Apr;12(4):991-5. doi: 10.1074/mcp.O112.026492. Epub 2013 Feb 1. PubMed PMID: 23378518; PubMed Central PMCID: PMC3617344.

Campbell MP, Ranzinger R, Lütteke T, Mariethoz J, Hayes CA, Zhang J, Akune Y, Aoki-Kinoshita KF, Damerell D, Carta G, York WS, Haslam SM, Narimatsu H, Rudd PM, Karlsson NG, Packer NH, Lisacek F. Toolboxes for a standardised and systematic study of glycans. BMC Bioinformatics. 2014;15 Suppl 1:S9. doi: 10.1186/1471-2105-15-S1-S9. Epub 2014 Jan 10. PubMed PMID:24564482; PubMed Central PMCID: PMC4016020.

Porterfield M, Zhao P, Han H, Cunningham J, Aoki K, Von Hoff DD, Demeure MJ, Pierce JM, Tiemeyer M, Wells L. Discrimination between adenocarcinoma and normal pancreatic ductal fluid by proteomic and glycomic analysis. J Proteome Res. 2014 Feb 7;13(2):395-407. doi: 10.1021/pr400422g. Epub 2013 Dec 12. PubMed PMID: 24328148; PubMed Central PMCID: PMC3946306.

Johnson D, Boyes B, Fields T, Kopkin R, Orlando R. Optimization of data-dependent acquisition parameters for coupling high-speed separations with LC-MS/MS for protein identifications. J Biomol Tech. 2013 Jul;24(2):62-72. doi: 10.7171/jbt.13-2402-003. PubMed PMID: 23814498; PubMed Central PMCID: PMC3605922.

Kang J, Shen Z, Lim JM, Handa H, Wells L, Tantin D. Regulation of Oct1/Pou2f1 transcription activity by O-GlcNAcylation. FASEB J. 2013 Jul;27(7):2807-17. doi: 10.1096/fj.12-220897. Epub 2013 Apr11. PubMed PMID: 23580612; PubMed Central PMCID: PMC3688745.

Wells L. The o-mannosylation pathway: glycosyltransferases and proteins implicated in congenital muscular dystrophy. J Biol Chem. 2013 Mar 8;288(10):6930-5. doi: 10.1074/jbc.R112.438978. Epub 2013 Jan 17. Review. PubMed PMID: 23329833; PubMed Central PMCID: PMC3591603.

Dobson CM, Hempel SJ, Stalnaker SH, Stuart R, Wells L. O- Mannosylation and human disease. Cell Mol Life Sci. 2013 Aug;70(16):2849-57. doi: 10.1007/s00018-012-1193-0. Epub 2012 Nov 1. Review. PubMed PMID: 23115008; PubMed Central PMCID: PMC3984002.

Aoki-Kinoshita KF, Bolleman J, Campbell MP, Kawano S, Kim JD, Lütteke T, Matsubara M, Okuda S, Ranzinger R, Sawaki H, Shikanai T, Shinmachi D, Suzuki Y, Toukach P, Yamada I, Packer NH, Narimatsu H. Introducing glycomics data into the Semantic Web. J Biomed Semantics. 2013 Nov 26;4(1):39. doi: 10.1186/2041-1480-4-39. PubMed PMID: 24280648; PubMed Central PMCID: PMC4177142.

Katayama T, Wilkinson MD, Aoki-Kinoshita KF, Kawashima S, Yamamoto Y, Yamaguchi A, Okamoto S, Kawano S, Kim JD, Wang Y, Wu H, Kano Y, Ono H, Bono H, Kocbek S, Aerts J, Akune Y, Antezana E, Arakawa K, Aranda B, Baran J, Bolleman J, Bonnal RJ, Buttigieg PL, Campbell MP, Chen YA, Chiba H, Cock PJ, Cohen KB, Constantin A, Duck G, Dumontier M, Fujisawa T, Fujiwara T, Goto N, Hoehndorf R, Igarashi Y, Itaya H, Ito M, Iwasaki W, Kalaš M, Katoda T, Kim T, Kokubu A, Komiyama Y, Kotera M, Laibe C, Lapp H, Lütteke T, Marshall MS, Mori T, Mori H, Morita M, Murakami K, Nakao M, Narimatsu H, Nishide H, Nishimura Y, Nystrom-Persson J, Ogishima S, Okamura Y, Okuda S, Oshita K, Packer NH, Prins P, Ranzinger R, Rocca-Serra P, Sansone S, Sawaki H, Shin SH, Splendiani A, Strozzi F, Tadaka S, Toukach P, Uchiyama I, Umezaki M, Vos R, Whetzel PL, Yamada I, Yamasaki C, Yamashita R, York WS, Zmasek CM, Kawamoto S, Takagi T. BioHackathon series in 2011 and 2012: penetration of ontology and linked data in life science domains. J Biomed Semantics. 2014 Feb 5;5(1):5. doi: 10.1186/2041-1480-5-5. PubMed PMID: 24495517; PubMed Central PMCID: PMC3978116.

Aoki-Kinoshita KF, Sawaki H, An HJ, Cho JW, Hsu D, Kato M, Kawano S, Kawasaki T, Khoo KH, Kim J, Kim JD, Li X, Lütteke T, Okuda S, Packer NH, Paulson JC, Raman R, Ranzinger R, Shen H, Shikanai T, Yamada I, Yang P, Yamaguchi Y, Ying W, Yoo JS, Zhang Y, Narimatsu H. The Third ACGG-DB Meeting Report: Towards an international collaborative infrastructure for glycobioinformatics. Glycobiology. 2013 Feb;23(2):144-6. doi: 10.1093/glycob/cws167. PubMed PMID: 23271684; PubMed Central PMCID: PMC3988462.

Panin VM, Wells L. Protein O-mannosylation in metazoan organisms. Curr Protoc Protein Sci. 2014 Feb 3;75:Unit 12.12.. doi: 10.1002/0471140864.ps1212s75. PubMed PMID: 24510673; PubMed Central PMCID: PMC3984005.

Wells L, Hart GW; Athens Guidelines for the Publication of Glycomics Data.. Glycomics: building upon proteomics to advance glycosciences. Mol Cell Proteomics. 2013 Apr;12(4):833-5. doi: 10.1074/mcp.E113.027904. Epub 2013 Feb 1. PubMed PMID: 23378519; PubMed Central PMCID: PMC3617329.

Mercado CP, Quintero MV, Li Y, Singh P, Byrd AK, Talabnin K, Ishihara M, Azadi P, Rusch NJ, Kuberan B, Maroteaux L, Kilic F. A serotonin-induced N-glycan switch regulates platelet aggregation. Sci Rep. 2013 Sep 30;3:2795. doi: 10.1038/srep02795. PubMed PMID: 24077408; PubMed Central PMCID: PMC3786303.

Kittur FS, Bah M, Archer-Hartmann S, Hung CY, Azadi P, Ishihara M, Sane DC, Xie J. Cytoprotective effect of recombinant human erythropoietin produced in transgenic tobacco plants. PLoS One. 2013 Oct 4;8(10):e76468. doi: 10.1371/journal.pone.0076468. eCollection 2013. PubMed PMID: 24124563; PubMed Central PMCID: PMC3790672.

Bubendorfer S, Ishihara M, Dohlich K, Heiss C, Vogel J, Sastre F, Panico M, Hitchen P, Dell A, Azadi P, Thormann KM. Analyzing the modification of the Shewanella oneidensis MR-1 flagellar filament. PLoS One. 2013 Sep 6;8(9):e73444. doi: 10.1371/journal.pone.0073444. eCollection 2013. PubMed PMID: 24039942; PubMed Central PMCID: PMC3765264.

Nasirikenari M, Veillon L, Collins CC, Azadi P, Lau JT. Remodeling of marrow hematopoietic stem and progenitor cells by non-self ST6Gal-1 sialyltransferase. J Biol Chem. 2014 Mar 7;289(10):7178- 89. doi: 10.1074/jbc.M113.508457. Epub 2014 Jan 14. PubMed PMID: 24425878; PubMed Central PMCID: PMC3945377.

DePaoli-Roach AA, Contreras CJ, Segvich DM, Heiss C, Ishihara M, Azadi P, Roach PJ. Glycogen phosphomonoester distribution in mouse models of the progressive myoclonic epilepsy, Lafora disease. J Biol Chem. 2015 Jan 9;290(2):841-50. doi: 10.1074/jbc.M114.607796. Epub 2014 Nov 21. PubMed PMID: 25416783; PubMed Central PMCID: PMC4294506.

Bammens R, Mehta N, Race V, Foulquier F, Jaeken J, Tiemeyer M, Steet R, Matthijs G, Flanagan-Steet H. Abnormal cartilage development and altered N-glycosylation in Tmem165-deficient zebrafish mirrors the phenotypes associated with TMEM165-CDG. Glycobiology. 2015 Jun;25(6):669-82. doi: 10.1093/glycob/cwv009. Epub 2015 Jan 21. PubMed PMID: 25609749; PubMed Central PMCID: PMC4410832.

Weigel PH, West CM, Zhao P, Wells L, Baggenstoss BA, Washburn JL. Hyaluronan synthase assembles chitin oligomers with -GlcNAc(α1→)UDP at the reducing end. Glycobiology. 2015 Jun;25(6):632-43. doi: 10.1093/glycob/cwv006. Epub 2015 Jan 12. PubMed PMID: 25583822; PubMed Central PMCID: PMC4410831.

Raval KK, Tao R, White BE, De Lange WJ, Koonce CH, Yu J, Kishnani PS, Thomson JA, Mosher DF, Ralphe JC, Kamp TJ.  Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes. J Biol Chem. 2015 Jan 30;290(5):3121-36. doi: 10.1074/jbc.M114.628628. Epub 2014 Dec 8. PubMed PMID: 25488666; PubMed Central PMCID: PMC4317045.

Dwyer CA, Katoh T, Tiemeyer M, Matthews RT. Neurons and glia modify receptor protein-tyrosine phosphatase ζ (RPTPζ)/phosphacan with cell-specific O-mannosyl glycans in the developing brain. J Biol Chem. 2015 Apr 17;290(16):10256-73. doi: 10.1074/jbc.M114.614099. Epub 2015 Mar 3. PubMed PMID: 25737452; PubMed Central PMCID: PMC4400340.

Al Jadda K, Porterfield MP, Bridger R, Heiss C, Tiemeyer M, Wells L, Miller JA, York WS, Ranzinger R. EUROCarbDB(CCRC): a EUROCarbDB node for storing glycomics standard data. Bioinformatics. 2015 Jan 15;31(2):242-5. doi: 10.1093/bioinformatics/btu609. Epub 2014 Sep 12. PubMed PMID: 25217575; PubMed Central PMCID: PMC4287942.

Chandler KB, Brnakova Z, Sanda M, Wang S, Stalnaker SH, Bridger R, Zhao P, Wells L, Edwards NJ, Goldman R. Site-specific glycan microheterogeneity of inter-alpha-trypsin inhibitor heavy chain H4. J Proteome Res. 2014 Jul 3;13(7):3314-29. doi: 10.1021/pr500394z. Epub 2014 Jun 12. PubMed PMID: 24884609; PubMed Central PMCID: PMC4084840.

Kunduri G, Yuan C, Parthibane V, Nyswaner KM, Kanwar R, Nagashima K, Britt SG, Mehta N, Kotu V, Porterfield M, Tiemeyer M, Dolph PJ, Acharya U, Acharya JK. Phosphatidic acid phospholipase A1 mediates ER-Golgi transit of a family of G protein-coupled receptors. J Cell Biol. 2014 Jul 7;206(1):79-95. doi: 10.1083/jcb.201405020. PubMed PMID: 25002678; PubMed Central PMCID: PMC4085702.

Lim JM, Wollaston-Hayden EE, Teo CF, Hausman D, Wells L.  Quantitative secretome and glycome of primary human adipocytes during insulin resistance. Clin Proteomics. 2014 May 12;11(1):20. doi: 10.1186/1559-0275-11-20. eCollection 2014. PubMed PMID: 24948903; PubMed Central PMCID: PMC4055909.